Skip to Content
Home > Patients & Visitors > Health Library > Multidrug-Resistant Tuberculosis (TB)
Multidrug-resistant tuberculosis (MDR-TB) occurs when the
bacteria are resistant to at least isoniazid and rifampin. This means that
these medicines are unable to kill the bacteria. The reasons
antibiotic resistance occurs include:
People who have resistant disease are at increased risk
for dying of TB, especially if they also are infected with the
human immunodeficiency virus (HIV). People who are at
highest risk for developing multidrug-resistant TB are those who:
To reduce the problem of drug resistance, doctors now use the
following guidelines to treat all people who have resistant TB:footnote 1
A rare type of MDR-TB is called extensively drug-resistant
tuberculosis (XDR-TB). This type of TB is resistant to isoniazid, rifampin, and
several other medicines used to treat TB. And some TB bacteria have become resistant to all of the antibiotics commonly used to treat TB. This is sometimes called totally resistant tuberculosis (TDR-TB).footnote 2
American Thoracic Society, Centers for Disease Control and Prevention, Infectious Diseases Society of America (2003). Treatment of tuberculosis. American Journal of Respiratory and Critical Care Medicine, 167(4): 603–662.
Cegielski P, et al. (2012). Challenges and controversies in defining totally drug-resistant tuberculosis. Emerging Infectious Diseases [Internet], November. Available online: http://wwwnc.cdc.gov/eid/article/18/11/12-0526_article.htm.
ByHealthwise StaffPrimary Medical ReviewerE. Gregory Thompson, MD - Internal MedicineSpecialist Medical ReviewerR. Steven Tharratt, MD, MPVM, FACP, FCCP - Pulmonology, Critical Care Medicine, Medical Toxicology
Current as ofMay 22, 2015
Current as of:
May 22, 2015
E. Gregory Thompson, MD - Internal Medicine & R. Steven Tharratt, MD, MPVM, FACP, FCCP - Pulmonology, Critical Care Medicine, Medical Toxicology
To learn more about Healthwise, visit Healthwise.org.
© 1995-2015 Healthwise, Incorporated. Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.
Feeling under the weather?
Use our interactive symptom checker to evaluate your symptoms and determine appropriate action or treatment.
Our interactive Decision Points guide you through making key health decisions by combining medical information with your personal information.
You'll find Decision Points to help you answer questions about:
Get started learning more about your health!
Our Interactive Tools can help you make smart decisions for a healthier life. You'll find personal calculators and tools for health and fitness, lifestyle checkups, and pregnancy.
Send Us Your Feedback
North Kansas City Hospital