Skip to Content
Home > Patients & Visitors > Health Library > Medicines for Erection Problems: Reactions With Nitrate
Phosphodiesterase-5 inhibitors, such as sildenafil
(for example, Viagra), have made a big difference in the
erection problems (erectile dysfunction). But they can
cause life-threatening side effects for anyone who also takes nitroglycerin or
another medicine containing an organic nitrate. This combination can make your
blood pressure fall too low. This can possibly cause a
heart attack, or death. Do not take nitrate medicines up to 24 hours after you take sildenafil (for example, Viagra) or vardenafil
(for example, Levitra). Do not take nitrate medicines up to 48 hours after you take tadalafil (for example, Cialis).
Medicines that contain organic nitrates include:
Nitrates found in foods are not a danger when taking
Other Works Consulted
Levine GN, et al. (2012). Sexual activity and cardiovascular disease: A scientific statement from the American Heart Association. Circulation, 125(8): 1058–1072.
Current as of:
June 4, 2014
E. Gregory Thompson, MD - Internal Medicine & Christopher G. Wood, MD, FACS - Urology, Oncology
How this information was developed to help you make better health decisions.
To learn more, visit Healthwise.org
© 1995-2014 Healthwise, Incorporated. Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.
Feeling under the weather?
Use our interactive symptom checker to evaluate your symptoms and determine appropriate action or treatment.
Our interactive Decision Points guide you through making key health decisions by combining medical information with your personal information.
You'll find Decision Points to help you answer questions about:
Get started learning more about your health!
Our Interactive Tools can help you make smart decisions for a healthier life. You'll find personal calculators and tools for health and fitness, lifestyle checkups, and pregnancy.
Send Us Your Feedback
North Kansas City Hospital.