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Transverse Myelitis

National Organization for Rare Disorders, Inc.

Important
It is possible that the main title of the report Transverse Myelitis is not the name you expected.

Disorder Subdivisions

  • Ascending Myelitis
  • Brown-Sequard Syndrome
  • Concussion Myelitis
  • Foix-Alajouanine Myelitis
  • Subacute Necrotizing Myelitis
  • Funicular Myelitis
  • Systemic Myelitis

General Discussion

Summary
Transverse myelitis (TM) is a rare inflammatory disease causing injury to the spinal cord with varying degrees of weakness, sensory alterations, and autonomic dysfunction (the part of the nervous system that controls involuntary activity, such as the heart, breathing, the digestive system, and reflexes).

Introduction
The first cases of acute myelitis were described in 1882 and were attributed to vascular lesions and acute inflammatory events. In England between 1922 and 1923 more than 200 postvaccinial cases were noted as complications of the smallpox and rabies vaccines. Later reports revealed that TM was post-infectious in nature, and agents including measles, rubella and mycoplasma were directly isolated from patient's spinal fluid. The term "acute transverse myelitis" was first used by an English neurologist in 1948 to describe a case of rapidly progressive paraparesis with a thoracic sensory level, occurring as a postinfectious complication of pneumonia. The Transverse Myelitis Consortium Working Group delineated diagnostic criteria for disease-associated TM and idiopathic TM along with a framework to differentiate TM from non-inflammatory myelopathies in 2002.

Resources

Transverse Myelitis Association
1787 Sutter Parkway
Powell, OH 43065-8806
USA
Tel: (614)766-1806
Email: info@myelitis.org
Internet: http://www.myelitis.org

Spinal Cord Society
19051 County Hwy. 1
Fergus Falls, MN 56537
USA
Tel: (218)739-5252
Fax: (218)739-5262
Email: scs-nc@nc.rr.com
Internet: http://www.spinalcordsociety.com

Academy of Spinal Cord Injury Professionals, Inc.
206 South Sixth Street, Springfield, IL 62701
Springfield, IL 62701
USA
Tel: (217)753-1190
Fax: (217)525-1271
Email: acheatham@firminc.com
Internet: http://www.academyscipro.org/

National Spinal Cord Injury Association
75-20 Astoria Blvd
Jackson Heights, NY 11370
USA
Tel: (718)803-3782
Tel: (800)962-9629
Email: info@spinalcord.org
Internet: http://www.spinalcord.org

NIH/National Institute of Neurological Disorders and Stroke
P.O. Box 5801
Bethesda, MD 20824
Tel: (301)496-5751
Fax: (301)402-2186
Tel: (800)352-9424
TDD: (301)468-5981
Internet: http://www.ninds.nih.gov/

Christopher & Dana Reeve Foundation
636 Morris Turnpike, Suite 3A
Short Hills, NJ 07078
USA
Tel: (973)379-2690
Fax: (973)912-9433
Tel: (800)225-0292
Email: prc@ChristopherReeve.org
Internet: http://www.christopherreeve.org

Genetic and Rare Diseases (GARD) Information Center
PO Box 8126
Gaithersburg, MD 20898-8126
Tel: (301)251-4925
Fax: (301)251-4911
Tel: (888)205-2311
TDD: (888)205-3223
Internet: http://rarediseases.info.nih.gov/GARD/

For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders (NORD). A copy of the complete report can be downloaded free from the NORD website for registered users. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational therapies (if available), and references from medical literature. For a full-text version of this topic, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".

The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.

It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report

This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.

For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site www.rarediseases.org or email orphan@rarediseases.org

Last Updated:  9/13/2012
Copyright  1988, 1989, 1996, 2004, 2012 National Organization for Rare Disorders, Inc.

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